Systemic cyclosporin A in high failure risk, repeated corneal transplantation

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منابع مشابه

Systemic cyclosporin A in high failure risk, repeated corneal transplantation.

AIM To evaluate the efficacy of oral cyclosporin A in the prevention and treatment of immune graft rejection in heavily vascularised, repeated keratoplasties with high risk for failure. METHODS 21 consecutive patients with 28 repeated corneal transplants and four quadrant vascularised recipient bed were treated with oral cyclosporin A for an average period of 12 months (range 1-41 months) and...

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CLINICAL SCIENCE Systemic cyclosporin A in high failure risk, repeated corneal transplantation

Aim: To evaluate the efficacy of oral cyclosporin A in the prevention and treatment of immune graft rejection in heavily vascularised, repeated keratoplasties with high risk for failure. Methods: 21 consecutive patients with 28 repeated corneal transplants and four quadrant vascularised recipient bed were treated with oral cyclosporin A for an average period of 12 months (range 1–41 months) and...

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Systemic Immunomodulatory Strategies in High-risk Corneal Transplantation

The cornea is the most commonly transplanted tissue in the body. Although corneal grafts generally have high success rates, transplantation onto inflamed and vascularized host beds, or so-called high-risk corneal transplantation, has a high rate of graft rejection. The management of this high-risk corneal transplantation is challenging and involves numerous measures. One of the key measures to ...

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Keratoprosthesis in high-risk pediatric corneal transplantation: first 2 cases.

Infantswithsignificantcornealopacitiesareat risk fordevelopmentofprofound deprivation amblyopia without surgical intervention. Early cornealtransplantationisrecommended. However, penetrating keratoplasty (PK) in young children is considered a high-risk procedure. Additionally, apoorerprognosishasbeendescribed in children with congenital corneal opacities when compared with acquired corneal opac...

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Systemic cyclosporin A in high risk penetrating keratoplasties: a case-control study.

AIM To examine the efficacy of systemic cyclosporin A (CSA) in preventing rejection and graft failure in high risk keratoplasty (PK). METHODS A retrospective case-control study with 49 patients in both the CSA group and the control group. The patients receiving CSA were at high risk of graft rejection and failure. Controls were identified from surgical audit books and had high risk characteri...

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ژورنال

عنوان ژورنال: British Journal of Ophthalmology

سال: 2002

ISSN: 0007-1161

DOI: 10.1136/bjo.86.9.988